Innate immunity and asthma risk in Amish and Hutterite farm children. BACKGROUND The Amish and Hutterites are U.S. agricultural populations whose lifestyles are remarkably similar in many respects but whose...
Land cover of early-life environment modulates the risk of type 1 diabetes. OBJECTIVE Environmental microbial exposures have been implicated to protect against immune-mediated diseases such as type 1 diabetes. Our...
Microbiome and type 1 diabetes. The steep increase in the incidence of type 1 diabetes (T1D), in the Western world after World War II, cannot be explained solely by genetic...
Urban environment predisposes dogs and their owners to allergic symptoms. Our companion-animals, dogs, suffer increasingly from non-communicable diseases, analogous to those common in humans, such as allergic manifestations. In humans,...
A biodiversity hypothesis. Biodiversity hypothesis states that contact with natural environments enriches the human microbiome, promotes immune balance and protects from allergy and inflammatory disorders. We are protected by two...
The rich and the poor: environmental biodiversity protecting from allergy Purpose of review It has been proposed that biodiversity loss leads to reduced interaction between environmental and human microbiotas. This,...
Immunological resilience and biodiversity for prevention of allergic diseases and asthma. Increase of allergic conditions has occurred at the same pace with the Great Acceleration, which stands for the rapid...
Environmental biodiversity, human microbiota, and allergy are interrelated. Rapidly declining biodiversity may be a contributing factor to another global megatrend—the rapidly increasing prevalence of allergies and other chronic inflammatory diseases...
Managing the allergy and asthma epidemic in 2020s—Lessons from the Finnish experience. In Finland, a systematic public health programme was implemented from 2008 to 2018 to mitigate the burden of...
The ‘Hygiene hypothesis’ Autoimmune and allergic diseases have become a major health problem in the Western world during past decades. The hygiene hypothesis suggests that decreased microbial exposure in childhood...